Comparative Pathology
The Comparative Pathology Shared Resource (CPSR), led by Dr. Davis Seelig, provides pathology support and expertise to Masonic Cancer Center members and non-members who use laboratory animals in their research.
We are a full-service pathology laboratory that offers support from the initial stages of the experiment (study design and preparation of research grant) through to the final stages (assisting with manuscript preparation after the results have been analyzed). We offer technical support for tissue collection, processing, and preparation of histological sections, and we also offer pathology support for interpretation and imaging of the tissues.
We are an a la carte laboratory that strives to meet the unique needs of our clientele regardless of the size and scope of the project. Investigators may use our resource for all of their comparative pathology needs or may request selected components (e.g., preparation of histological sections from a previously prepared tissue block or staining previously prepared glass slides).
Services
Areas of research:
- Cancer
- Immunology
- Infectious disease
- Metabolic diseases
- Genetic diseases
- Toxicology
- Medical devices
- Regulatory pathology
- Organoid pathology
Areas of technical support:
- Fixed and frozen tissue processing, embedding, staining (routine and immunohistochemistry), and whole slide scanning.
- Antibody validation and immunohistochemical protocol development.
- Comprehensive pathology support – including consultation, project planning, grant preparation, sample collection and analysis, and customized report generation.
- Quantitative tissue analysis using the HALO image analysis platform.
Common Laboratory Species
- Mouse
- Rat
- Hamster
- Guinea pig
- Rabbit
- Pig
- Non-human primate
Our pathologists have comprehensive training across numerous species. If you work with a non-traditional laboratory animal, please contact us to discuss how we can assist you.