Pre-R01 Brainstorm Award

The objective of the Brainstorm Awards is to foster interdisciplinary collaborations encompassing novel, hypothesis-driven studies of cancer or a cancer-related topic. Proposed projects must be joint, collaborative efforts by at least two Cancer Center members from different programs or different disciplines, and must represent a new collaborative proposal.

Grantees

2023

The Role of Immunosenescence in Delayed Anthracycline-induced Cardiac Complications
Beshay Zordoky, PhD, Department of Experimental and Clinical Pharmacology, College of Pharmacy

Christina Camell, PhD, Department of Biochemistry, Molecular Biology and Biophysics, College of Science and Engineering
Karim Sadak, MD, MPH, MSE, Division of Pediatric Hematology and Oncology, Medical School

Uncovering mechanisms of PARP inhibitor sensitivity in SF3B1-mutant cancers
Hai Dang Nguyen, PhD, Department of Pharmacology, Medical School

Nuri Alpay Temiz, PhD, Institute for Health Informatics, Office of Academic and Clinical Affairs

2022

The role of the proteasome in TP53 mutant AML self-renewal
Zohar Sachs, MD, PhD, Division of Hematology, Oncology and Transplantation, Medical School

Do-Hyung Kim, PhD, Biochemistry, Molecular Biology, and Biophysics, College of Biological Sciences

Oncolytic Adenovirus-Mediated Viroimmunotherapy and Imaging for ER+ Breast Cancer
Julia Davydova, MD, PhD, Department of Surgery, Medical School

Julie Ostrander, PhD, Division of Hematology, Oncology and Transplantation, Medical School
Anne Blaes, MD, Division of Hematology, Oncology and Transplantation, Medical School
Christopher LaRocca, MD, Division of Surgical Oncology, Medical School
Zuzan Cayci, MD, Department of Radiology, Medical School

2021

Roles of tumor-microenvironment Lyn kinase in breast-cancer metastasis
Tanya Freedman, PhD, Department of Pharmacology, Medical School

Targeting Gliomas with Chemically Self-Assembled Nanoring T-cell Engagers (CSAN-TE)
Carston Wagner, PhD, Medicinal Chemistry, College of Pharmacy

2020

Defining RHAMM (Receptor for Hyaluronan Mediated Motility) as a Progression-Promoting and Targetable Biomarker in Triple Negative Breast Cancer
Andrew Nelson, MD, PhD, Laboratory Medicine and Pathology, Medical School

James McCarthy, PhD, Laboratory Medicine and Pathology, Medical School

2019

Enhancing T cell functionality in pancreatic ductal adenocarcinoma
Ingunn Stromnes, PhD, Microbiology and Immunology, Medical Schoo

Therapeutic vulnerabilities in acute myeloid leukemia stem cells with TP53 alterations
Zohar Sach, MD, PhD, Division of Hematology, Oncology and Transplantation, Medical School

Fiona He, MD, Division of Hematology, Oncology and Transplantation, Medical School
Chad Myer, PhD, Department of Computer Science and Engineering

2018

4D Engineered In Vitro Models of Metastasis and Drug Screening
Angela Panoskaltsis-Mortari, PhD, Department of Pediatrics, Medical School
Michael McAlpine, PhD, Department of Mechanical Engineering, College of Science and Engineering

Enhancing pancreatic cancer immunotherapy through parallel murine and human tumor antigen receptor engineering
Beau Webber, PhD, Department of Pediatrics, Medical School
Ingunn Stromnes, PhD, Department of Microbiology and Immunology, Medical School 

Potentiation of Immune Checkpoint Blockade by Inhibition of Epoxyeicosatrienoic Acid Driven Tumor Respiration
David Potter, MD, PhD, Department of Medicine, Medical School
Michael Farrar, PhD, Department of Laboratory Medicine and Pathology, Medical School

2017

Molecular dissection of PELP1 protein interactions

Julie Ostrander, PhD, Department of Medicine, Medical School
Hideki Aihara, PhD, Department of Biochemistry, Molecular Biology, and Biophysics, Medical School
 
Using adrenergic receptor antagonists to inhibit sarcoma growth and enhance T cell responses
Erin Dickerson, PhD, Department of Veterinary Clinical Sciences, College of Veterinary Medicine
Stephen Jameson, PhD, Department of Laboratory Medicine and Pathology, Medical School
2016

Tumor-infiltrating Eosinophils: A Protective Role in Colorectal Cancer
Anna Prizment, PhD, Epidemiology and Community Health, School of Public Health
Robert Cormier, PhD, Department of Biomedical Sciences, Medical School, UMD

The Development of a PEG10 Promoter Driven Theranostic for Castration-Resistant Prostate Cancer
Aaron LeBeau, PhD, Department of Pharmacology, Medical School
Gregory Metzger, PhD, Department of Radiology, Medical School

2014

A Paradoxical Role for Hypoxia-Inducible Factor Signaling in Pancreas Cancer
Paolo Provenzano, PhD, Department of Biomedical Engineering, College of Science and Engineering
Anindya Bagchi, PhD, Department of Urology, Medical School

Targeting Deubiquinating Enzymes (DUBs) as Therapeutic Targets to Overcome Drug Resistance in Diverse Cancers
Brian VanNess, PhD, Department of Genetics, Cell Biology and Development, College of Biological Sciences
Martina Bazzaro, PhD, Department of Obstetrics, Gynecology and Women’s Health, Medical School

2013

Improved NK Cell-mediated Anti-ovarian Cancer Response via Disruption of CD16a Down-regulation
Daniel Kaufman, MD, PhD, Department of Medicine, Medical School
Bruce Walcheck, PhD, Department of Veterinary and Biomedical Sciences, College of Veterinary Medicine

Synthetic Inhibitors of CD44/Hyaluronan Interactions
James McCarthy, PhD, Department of Laboratory Medicine and Pathology, Medical School
Barry Finzel, PhD, Department of Medicinal Chemistry, College of Pharmacy 

2012

Comparative Analysis of Repair and Checkpoint Capacities of Fanconi Anemia Cells
Anja Bielinsky, PhD, Department of Biochemistry, Molecular Biology, and Biophysics, College of Biological Sciences
Jakub Tolar, MD, PhD, Department of Pediatrics, Medical School

Development of Novel Monocarboxylate Transporter-1 Inhibitors for the Treatment of Gliomas
Lester Drewes, PhD, Department of Biomedical Sciences, Medical School, UMD
Venkatram Mereddy, PhD, College of Pharmacy, UMD

2011

Mechanism of Action and Prodrugs of RITA, a Small Molecule for MLL Leukemias
Robert Fecik, PhD, Department of Medicinal Chemistry, College of Pharmacy
John Kersey, MD, Department of Laboratory Medicine and Pathology, Medical School

Integration of Docetaxel into Nanorings for the Treatment of Prostate Cancer
Carston Wagner, PhD, Department of Medicinal Chemistry, College of Pharmacy
Gunda Georg, PhD, Department of Medicinal Chemistry, College of Pharmacy

2010

Proteomic Detection of Ovarian Cancer Biomarkers in Routine Pap Tests
Amy Skubitz, PhD, Department of Laboratory Medicine and Pathology, Medical School
Melissa Geller, MD, Department of Obstetrics, Gynecology and Women’s Health, Medical School

DNA-protein Cross-linking in Carcinogenesis and Antitumor Therapy
Natalia Tretyakova, PhD, Department of Medicinal Chemistry, College of Pharmacy
Colin Campbell, PhD, Department of Pharmacology, Medical School