The primary aim of the Clinical Informatics Shared Services (CISS) is to provide state-of-the-art centralized clinical informatics services for the support of Masonic Cancer Center operations, research, and quality of care improvement effort. These services include access to rich clinical and genomics database, data extraction and preparations, secure and robust informatics infrastructure, advanced analytics, application development as well as collaborative science opportunities with highly qualified informatics consultants and faculty.
Access to Data:
Dataset Preparation & Extraction:
|Data repositories & registries
Natural Language Processing:
Academic Health Center Information Exchange (AHC-IE):
- Clinical EMR data for ~ 2.5M Fairview and University of Minnesota Physicians (UMP) patients.
- Genomics data
OptumLabs Data Warehouse (OLDW):
- De-identified claims and electronic health records data for >150M lives (20% with EMR).
- OnCore® enterprise CTMS:
Extraction of Clinical Trial Data that are managed by OnCore® enterprise CTMS
- AaxiUm records through School of Dentistry (in progress)
- Master Death Index:
- Death Certificates through Minnesota Department of Health
- Census data at the block group level from the 2010 Census.
- The Clinical EMR data is geocoded and enhanced latitude/longitude/block data elements
- Standard Terminology and code sets including ICD-9/10, LOINC, NDF-RT, RxNorm, CPT, HCPCS
Masonic Cancer Center Data Registries and Repositories
- Bone Marrow Transplant database (BMT): Blood and Marrow Transplant database used by the Cancer Center to capture post-transplant outcome data on subjects.
- Laboratory information management system (LIMS): Subjects’ samples processed data based on study objective. For Example: number of aliquots, analyte, pre and post Ficoll.
- FreezerWorks: Research samples freezer inventory data. Such as: Freezer name, shelf, rows, box etc.
Rates and Publications
CISS provides consultation free of charge to all MCC members to help prepare the informatics resource sections for grant applications and to provide initial cost estimates for other informatics projects.
Extended collaboration with the Informatics team should be directly supported by the appropriate funding sources. Costs for services are recovered through percent effort of personnel or through the ISO model.
Publications resulting from informatics work should merit co-authorship: the order of authorship is up to the principal investigator/primary author.
More often, our staff members may serve as collaborative partners in the development of custom databases and analysis pipelines involving large data sets generated in high throughput projects.
Complete a: request form for informatic services
Services We Offer
- Projects that provide funding for Cancer Informatics experts in the core
- Grant preparation
- Data analysis for cancer-related projects
- Design experiments involving large-scale molecular studies
- Referrals to MSI software and staff for other molecular studies
- Referrals to external software sources (e.g., EnsEMBL, FANTOM)
- Write bioinformatic components of grant proposals
- Identify leading-edge technologies to be incorporated in research plans
- Conduct analysis of high throughput molecular data (e.g., mRNA, miRNA, insertional mutagenesis studies, ChIP-seq)
- Assist with the interpretation of results
- Recommend presentation and visualization methods
- Author bioinformatics component of manuscripts