Margaret MacMillan, MD, MSc, FRCPC
United States
Administrative support contact for Dr. MacMillan: Joyce Selle
Dr. MacMillan is Professor in Pediatrics and Division Director of the Pediatric Blood and Marrow Transplantation & Cellular Therapy Program at the University of Minnesota. Dr. MacMillan received her MSc and MD from the University of Toronto in 1991. She completed residency in Pediatrics and a fellowship in Pediatric Hematology and Oncology at the Hospital for Sick Children at the University of Toronto in 1997. She then completed a fellowship in Pediatric Blood and Marrow Transplantation at the University of Minnesota and joined the faculty in 1999.
Dr. MacMillan's clinical focus is allogeneic hematopoietic cell transplantation for children with malignant and non-malignant diseases, especially Fanconi anemia. Dr. MacMillan is Director of the Kidz1stFund Comprehensive Fanconi Anemia Center at the University of Minnesota, which funds innovative cellular and gene therapy research for Fanconi anemia. Her research interests also include graft-versus-host disease (GVHD), especially the development and implementation of novel strategies to prevent and treat acute GVHD, and the optimization of acute GVHD clinical trial design by determining GVHD risk and best trial endpoints.
She is the principal investigator of 12 phase I/II clinical trials at the University of Minnesota and a key co-investigator on several other trials including several multicenter trials. Dr. MacMillan holds 3 INDs for cellular therapy and has an excellent understanding of the regulatory requirements of translational research. She has authored more than 200 peer-reviewed manuscripts and book chapters.
Dr. MacMillan has served on several national committees including past Director-at-Large for the American Society for Transplantation and Cellular Therapy (ASTCT) and current CIBMTR GVHD Working Committee Co-Chair. Dr. MacMillan is Chair of the IRB for the National Marrow Donor Program, Co-Director of the ASTCT Clinical Research Training Course, and an Associate Editor of Transplantation and Cellular Therapy.