Karen Wyckoff Rein in Sarcoma Research Grant
The Karen Wyckoff Rein in Sarcoma Foundation was established by Karen Wyckoff shortly before her death from synovial sarcoma in August of 2001. These research grants support one of the three major goals of the foundation (research; patient and survivor support; and education) to continue Karen’s vision. Proposals must focus primarily on sarcoma (basic, translational and/or clinical research).
Targeting the Cell Cycle and Autophagy Reciprocal Communication Pathways in Sarcomas
Erin Dickerson, PhD, Veterinary Clinical Sciences, College of Veterinary Medicine
Characterization of Ewing sarcoma patient-derived induced pluripotent stem cells
Beau Webber, PhD, Division of Hematology, Oncology and Transplantation, Medical School
Identifying and Characterizing the Cells that Create the Primary and Metastatic Sarcoma Niche
Jaime Modiano, VMD, PhD, Veterinary Clinical Sciences, College of Veterinary Medicine
Using propranolol to generate an anti-tumor immune microenvironment
Erin Dickerson, PhD, Veterinary Clinical Sciences, College of Veterinary Medicine
eBAT as a Modulator of the Myeloid Immune Checkpoint in Cancer
Jaime Modiano, VMD, PhD, Veterinary Clinical Sciences, College of Veterinary Medicine
Computationally Deciphering the Paths of Genomic Catastrophe in Osteosarcoma
Ruping Sun, PhD, Laboratory Medicine and Pathology, Medical School
HH signaling genetic alterations: A relevant and targetable trait in peripheral nerve sheath sarcomas
David Largaespada, PhD, Division of Hematology, Oncology and Transplantation, Medical School
Registry-based analysis of risk and survival for young-onset sarcomas
Logan Spector, PhD, Pediatrics, Epidemiology and Clinical Research, Medical School
MYOG Promoter-Controlled Oncolytic Adenovirus to Treat PAX3-FOXO1-Positive Rhabdomyosarcoma
Masato Yamamoto, PhD, Department of Surgery, Medical School
Reprogramming cholesterol metabolism in sarcomas using adrenergic receptor antagonists
Erin Dickerson, PhD, Veterinary Clinical Sciences, College of Veterinary Medicine
Retrospective and prospective comparison of prognostic transcriptional biomarkers in osteosarcoma using nanostring RNA profiling
Aaron Sarver, PhD, Institute for Health Informatics, Office of Academic Clinical Affairs
Predicting relapse and response to chemotherapy in sarcoma
Amy Skubitz, PhD, Department of Laboratory Medicine & Pathology, Medical School
Identification of novel drivers of Ewing Sarcoma through engineered transformation of cells with differing levels of African admixture
Beau Webber, PhD, Division of Hematology, Oncology and Transplantation, Medical School
Engaging the Immune System as a Strategy for Sarcoma Therapy
Antonella Borgatti, DVM, MS, Veterinary Clinical Sciences, College of Veterinary Medicine
Enhancement of the response of sarcoma to SBRT by targeting HIF-lα
L. Chinsoo Cho, MD, Department of Radiation Oncology, Medical School
Effects of beta-adrenergic receptor antagonists on sarcoma radiosensitivity
Jessica Lawrence, DVM, DACVIM, Department of Radiation Oncology, Medical School