A scientist in a lab coat and gloves uses a tablet displaying medical data next to a microscope and test tubes filled with colorful liquids.

Analytical Biochemistry & Mass Spectrometry

The laboratory provides researchers with state-of-the-art instruments and highly experienced personnel to support the development and use of qualitative and quantitative assays for the detection of a broad range of analytes across a variety of biological specimens and physiologic fluids. We operate as an open-access core laboratory, encouraging users to run their own samples. 

We work closely with our users to successfully perform the analysis they require to support their research, within the capabilities of the laboratory instrumentation and the staff's expertise. The laboratory has developed a wide range of capabilities over the course of its history, and we work to ensure our users have access to state-of-the-art analytical and data analysis tools to support the ever-increasing analytical power of modern mass spectrometry.  

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Services

  • Small molecule quantitation
  • Structural characterization/accurate mass determination
  • DNA adductomics
  • Proteomics
  • Metabolomics/Lipidomics
  • Macromolecule characterization
  • Intact proteins
  • Oligonucleotides
  • Metal analysis

Instrumentation

LC-MS
Orbitraps (High Resolution/Accurate Mass)

  • Exploris 480
  • Lumos, Fusion
  • Elite, Velos

Triple Quadrupoles

  • Quantiva, Vantage, Discovery Ultra

Ion Trap

  • LTQ

GC-MS

  • TSQ 9000 (Triple Quad)
  • ISQ 7000 (Single Quad)

ICP-MS

  • iCAP TQe
  • Elan DRC II