Masonic Cancer Center

A comprehensive cancer center designated by the National Cancer Institute

Masonic Cancer Center Update Newsletter


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Update is an official newsletter of the Masonic Cancer Center for faculty, members, staff, colleagues, and friends. All submissions for the next issue must be sent to, by noon on Thursday for publication the following Monday.

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April 27, 2015

Tuesday's Seminar 

Tuesday, April 28, 2015, 9-10 a.m., 1-125 CCRB
Peter Gordon, M.D., Ph.D., Assistant Professor, Department of Pediatrics, Division of Hematology/Oncology, University of Minnesota

This meeting will be simulcast in 450 MCRB.

A peek at next week’s seminar:


Tuesday, May 5, 2015, 9-10 a.m., 1-125 CCRB
Transcriptional activation and developmental regulation via chromatin remodeling machines
Chief, Epigenetics & Stem Cell Biology Laboratory, Principal Investigator, National Institute for Environmental Health Sciences


Host: Carol Lange, Ph.D. and Cancer Biology Training Grant


View the calendar for a complete schedule.

In This Issue

Message from the Director


Program Meetings

Professional Education


Funding Announcements and Opportunities

Message from the Director

As you know, human subject research at the University of Minnesota has been under scrutiny and the U has suspended recruitment to studies in the Department of Psychiatry while implementation of a review panel’s recommendations is underway.  Since the issues are complex, Dr. Brooks Jackson, vice president for health sciences and dean of the medical school, will convene a town hall meeting on Monday, May 4, 2015 at 3:55 p.m. in the Mayo Auditorium. This meeting is open to the public. 

Since clinical research is the cornerstone of what we in the Masonic Cancer Center do, I would like to see a strong contingent of MCC members and researchers in attendance at this town hall. We will gather together in the 4th floor atrium of the MCRB at 3 p.m. for snacks and some preparatory discussion on the contributions we can make to this discussion, and will leave for the meeting at 3:30. 

Please make every effort to be there.

Douglas Yee, M.D.


Members in the news

Michael Farrar, Ph.D., Immunology Program, is mentioned in a Health News Digest story about research that discovered a new pathway that prevents chronic inflammation in the gut.

Todd Tuttle, M.D., Prevention and Etiology program is quoted in ReutersNewsmax Healthstories on how worry may drive low-risk cancer patients to want double mastectomies. 

Jakub Tolar, M.D., Ph.D., Transplant Biology and Therapy Program member and director of the University of Minnesota Stem Cell Institute in mentioned in a MN Daily story on the growing support for stem cell research at the capitol.

Congratulations to Anne Joseph, M.D., M.P.H., co-leader, Prevention and Etiology Program, on her appointment as the inaugural Vice-Chair for Faculty Affairs and Diversity at the new Office of Faculty Affairs and Diversity in the Department of Medicine

Members in the journals

A paper by a team of investigators led by Scott Dehm, Ph.D., Cell Signaling Program, "Targeting chromatin binding regulation of constitutively active AR variants to overcome prostate cancer resistance to endocrine-based therapies," was published in Nucleic Acids Research as a “Breakthrough” article. The study identified a new mechanism of action that could lead to clinical intervention in cases of advanced, therapy-resistant prostate cancer. A press release from Nucleic Acids Research noted, “Reviewers who evaluated the study stated that it ‘settles considerable historical controversy in its field, related
to the significance of these truncated proteins" and will fundamentally advance understanding of the biological features of hormone-resistant cancer cells.’”

A paper from the laboratories of Ashok Saluja, Ph.D., Cell Signaling Program, and Subbaya Subramanian, Ph.D.,Genetic Mechanisms of Cancer Program, on “Triptolide abrogates growth of colon cancer and induces cell cycle arrest by inhibiting transcriptional activation of E2F,” was published in Laboratory Investigation, the official journal of the U.S. and Canadian Academy of Pathology.

Members at conferences
Antonella Borgatti, D.V.M., presented a poster entitled, "Genetically engineered targeted toxin enhances survival in dogs with naturally-occurring, incurable hemangiosarcoma," on April 20, 2015, at the annual meeting of the American Association for Cancer Research in Philadelphia, PA.

May 5th is the deadline to register for Race for the Cure team
The deadline to register for a team to participate in the Susan G. Komen Race for the Cure on May 10 is Monday, May 5. The Masonic Cancer Center has a team, the “Runnin’ Receptors” with Douglas Yee, M.D. as the captain! 

There are also volunteer opportunities for the UMN Cancer Care team - Masonic Cancer Center, University of Minnesota Cancer Care, and Fairview - to hold up signs and cheer participants. There are two shifts – 7-8:30 a.m. for the run and 9-10:30 a.m. for the walk. To sign up to join us at the Race, please email Kelly Schultz at by Friday, May 1 with your desired shift(s), name, names of any family members attending and t-shirt sizes for all.

Predoctoral training fellowship available
A predoctoral training fellowship is immediately available in the Institute for Molecular Virology Training Program (IMVTP. The overarching research theme of the IMVTP is virus-host cell interactions, which encompasses 1) mechanisms of viral replication and restriction
and 2) viral molecular pathogenesis. The application deadline is Monday, May 8 at 5 p.m. Contact for more information.

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Program Meetings

BMT Program
Monday, may 4, 1:15-2:15 p.m., 450 MCRB
Developing new cellular therapies to treat GVHD following stem cell transplantation
Keli Hippen, Ph.D., Assistant Professor, Department of Pediatrics

Professional Education

April 30, 2015: Introduction to Crispr/Cas9 Genome Editing Technology
4-5 p.m., 450 MCRB
The Center for Genome Editing and the Mouse Genetics Laboratory invite you to attend our seminar discussing applications and technical optimization of the Crispr/Cas9 genome editing technology. Crispr/Cas9 genome editing can be used to generate targeted mouse models including Knockouts, Conditional Knockouts and Knockin models. Short presentations from Branden Moriarity (CGE), Beau Webber (SCI) and Satyabrata Das (LHI) will highlight recent U of M projects using Crispr/Cas 9 targeting. After the presentations, we will have an extended question and answer opportunity so that interested investigators can discuss their specific interest in using Crispr/Cas9. Contact Sandi Wagner, for more information.

May 1, 2015: Cancer Detection, Treatment and Survivorship Special Seminar
10-11 a.m., 450 MCRB
Garibaldi Research Conference, Division of Hematology, Oncology and Transplantation
Identifying, preventing and remediating frail health after treatment for childhood cancer
Kirsten Ness, P.T., Ph.D., Associate member, Department of Epidemiology and Cancer Control and Department of Pediatric Medicine, St. Jude Children's Hospital

May 4, 2015: Academic Health Center Human Research Subjects Town Hall Meeting
3:55-4:55 p.m., Mayo Auditorium
Brooks Jackson, M.D., Vice-president, Academic Health Center and Dean, Medical School
Join the livestream at

May 8, 2015: Department of Pharmaceutics Guest Seminar
3:30-4:30 p.m., Room 5-125 Moos Tower
Engineered proteins for visualizing and treating disease
Jennifer  Cochran, Ph.D., Associate Professor of Bioengineering and Chemical Engineering, Hitachi America Family Scholar, Schools of Engineering and Medicine, Stanford University

May 12, 2015: Conversation with the Director of Research Engagement
1:30-2:30 p.m., 260 Social Sciences (West Bank)
Join the Research Development Community of Practice group in a conversation with
OVPR Director of Research Engagement and Humphrey School of Public Affairs Associate Professor Carissa Slotterback.
Last fall OVPR created the new position of Director of Research Engagement to facilitate greater connections among researchers across the university and beyond. As this is a joint endeavor that for many of us constitutes a major goal in our own work with the research community in our respective units, we look forward to exploring how we can all work more closely with each other and the OVPR to advance research engagement initiatives at the University and within our own colleges and departments. Email questions to Ana Brailovsky,

May 20, 2015: 15th Annual BioResearch Product Faire
10 a.m.-2:30 p.m., Great Hall, Coffman Memorial Union

June 8, 2015: Department of Radiology Grand Rounds
5 p.m., Leo Rigler Conference Room, May B-216
Images are data, not pictures: Radiomics of cancers
Robert Gillies, M.D., Moffitt Cancer Center, Vice-chair of Radiology, Director, Experimental Imaging Program

June 24, 2015: 24th Annual Mark E. Nesbit Lectureship in Pediatric Oncology
12:15 p.m., Conference Center, University of Minnesota Masonic Children’s Hospital
Speaker: David Malkin, M.D., Senior Staff Oncologist in Hematology/Oncology at The Hospital for Sick Children, Director, Cancer Genetics Program, Professor, Department of Pediatrics, University of Toronto

Visit the Education and Training Opportunities web page for more conference and special lecture listings.

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May 2, 2015: Cancer Survivorship Conference
8:30 a.m.- 1 p.m., McNamara Alumni Center, University of Minnesota, 200 Oak St. SE Minneapolis, MN 55455
The 10th Annual Cancer Survivorship Conference which will address topics important to cancer survivors and their families. Cancer survivors ages 16 and older, parents, spouses, significant others, health care professionals, school administrators and social workers can benefit from this educational conference. View or download the brochure. (PDF)

There is no fee to attend, but reservations are required. A free continental breakfast and lunch will be served. Space is limited, so please register early or call 1-888-CANCERMN (1-888-226-2376).

May 10, 2015: Susan G. Komen Race for the Cure®
7 a.m.-10:30 a.m., Southdale Center

May 30, 2015: Break the Bank for Kidney Cancer
TCF Bank Stadium: Race check-in 15-45 minutes prior to heat near Minnesota Tribal Nations Plaza, (West end of the stadium).
Racing climbers and Burly Bank climbers start at 7 a.m. Participant climbers start at 9 a.m. 

Break the Bank- Climb 4 Kidney Cancer, is a professionally managed event with a chip-timed race early in the morning, and a non-competitive fun climb. Children under the age of 10 are welcome to climb with adult supervision, but are not allowed in the race portion of the climb.

View a video with Coach Jerry Kill.
Visit the website for more information and to register.

June 20, 2015: 13th Annual Time to Fly ® Walk/Run
Phalen Park, St. Paul

Visit the Community Events and Outreach page for more information.

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Funding Announcements and Opportunities

Learn About the New NIH Biosketch Format
Come join Frances Spalding from the Sponsored Projects Administration Office, and Katherine Chew from the Biomedical Library as they present information on the new biosketch and demonstrate SciENcv, the new electronic system for creating biographical sketches for federal grants. All are welcome!
Wednesday, May 27, 10-11 a.m., 100 Murphy Hall. East Bank

U Libraries data sharing workshops
University Libraries will offer Data Sharing in the Sciences (May 18, 20, & 21; various times)- workshops that will address the different options for data sharing and archiving, data management strategies needed to create sharable and/or archival data, and other concerns.

Funding Opportunities:

2015 Academic Health Center Faculty Research Development (AHC-FRD) Grant Program (pdf)
The Academic Health Center (AHC) is soliciting applications for Faculty Research Development (FRD) grants. These grants will be awarded through a competitive peer review process. It is anticipated that up to six projects will be funded in the current competition. FRD grants are intended to support new or expanding interdisciplinary research, which is innovative and has a high potential for return on investment.
LOI Deadline: May 29th, 2015
Full Application Deadline: June 12th, 2015
Funding: $200,000 applied to 1 or 2 year project

JUST RELEASED!  FY15 DOD Lung Cancer Research Program and Peer Reviewed Medical Research Program
Recently released funding opportunities are available now for the Lung Cancer Research Program:

Career Development Award
Clinical Exploration Award
Idea Development Award

Peer Reviewed Medical Research Program:

Clinical Trial Award
Discovery Award
Focused Program Award
Investigator-Initiated Research Award
Technology/Therapeutic Development Award

Detailed descriptions of the funding opportunity, evaluation criteria, and submission requirements can be found in the Program Announcements.

Visit the Funding Opportunities Web page to see listings previously published in Update. A list of organizations that provide funding for cancer research is also provided there.

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  • Last modified on April 27, 2015